Hydrodynamic and Aerodynamic Tests of Models of Flying-boat Hulls Designed Flow Aerodynamic Drag - NACA Models 74, 74-A, and 75

The present tests illustrate how the aerodynamic drag of a flying boat hull may be reduced by following closely the form of a low drag aerodynamic body and the manner in which the extent of the aerodynamic refinement is limited by poorer hydrodynamic performance. This limit is not sharply defined but is first evidenced by an abnormal flow of water over certain parts of the form accompanied by a sharp increase in resistance. In the case of models 74-A and 75, the resistance (sticking) occurs only at certain combinations of speed, load, and trim and can be avoided by proper control of the trim at high water speeds. Model 75 has higher water resistance at very high speeds than does model 74-A. With constant speed propellers and high takeoff speeds, it appears that the form of model 75 would give slightly better takeoff performance. Model 74-A, however, has lower aerodynamic drag than does model 75 for the same volume of hull

The effect of the spin-orbit interaction on the band gap of half-metals

The spin-orbit interaction can cause a nonvanishing density of states (DOS) within the minority-spin band gap of half-metals around the Fermi level. We examine the magnitude of the effect in Heusler alloys, zinc-blende half metals and diluted magnetic semiconductors, using first-principles calculations. We find that the ratio of spin-down to spin-up DOS at the Fermi level can range from below 1% (e.g. 0.5% for NiMnSb) over several percents (4.2% for (Ga,Mn)As) to 13% for MnBi.Comment: 5 pages, 3 figure

Cabibbo-allowed nonleptonic weak decays of charmed baryons

Cabibbo-allowed nonleptonic weak decays of charmed baryons \lamc,~\xin,~\xip and $\Omega_c^0$ into an octet baryon and a pseudoscalar meson are analyzed. The nonfactorizable contributions are evaluated under pole approximation, and it turns out that the $s$-wave amplitudes are dominated by the low-lying \halfm resonances, while $p$-wave ones governed by the ground-state \halfp poles. The MIT bag model is employed to calculate the coupling constants, form factors and baryon matrix elements. Our conclusions are: (i) $s$ waves are no longer dominated by commutator terms; the current-algebra method is certainly not applicable to parity-violating amplitudes, (ii) nonfactorizable $W$ exchange effects are generally important; they can be comparable to and somtimes even dominate over factorizable contributions, depending on the decay modes under consideration, (iii) large-$N_c$ approximation for factorizable amplitudes also works in the heavy baryon sector and it accounts for the color nonsuppression of \lamc\ri p\bar{K}^0 relative to \lamc\ri\Lambda\pi^+, (iv) a measurement of the decay rate and the sign of the $\alpha$ asymmetry parameter of certain proposed decay modes will help discern various models; especially the sign of $\alpha$ in \lamc\ri\Sigma\pi decays can be used to unambiguously differentiate recent theoretical schemes from current algebra, and (v) $p$ waves are the dominant contributions to the decays \lamc\ri\Xi^0 K^+ and \xin\ri\Sigma^+ K^-, but they are subject to a large cancellation; this renders present theoretical predictions on these two channels unreliable.Comment: PHYZZX, 31 pages, 3 tables, IP-ASTP-10-93, ITP-SB-93-2

Processing and Transmission of Information

Contains reports on seven research projects.Lincoln Laboratory, Purchase Order DDL B-00337U.S. ArmyU.S. NavyU.S. Air Force under Air Force Contract AF19(604)-7400National Institutes of Health (Grant MH-04737-02

Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence

Candida albicans is an opportunistic fungus responsible for the majority of systemic fungal infections. Multiple factors contribute to C. albicans pathogenicity. C. albicans strains lacking CaArv1 are avirulent. Arv1 has a conserved Arv1 homology domain (AHD) that has a zinc-binding domain containing two cysteine clusters. Here, we explored the role of the CaAHD and zinc-binding motif in CaArv1-dependent virulence. Overall, we found that the CaAHD was necessary but not sufficient for cells to be virulent, whereas the zinc-binding domain was essential, as Caarv1/Caarv1 cells expressing the full-length zinc-binding domain mutants, Caarv1C3S and Caarv1C28S, were avirulent. Phenotypically, we found a direct correlation between the avirulence of Caarv1/Caarv1, Caarrv1AHD, Caarv1C3S, and Caarv1C28S cells and defects in bud site selection, septa formation and localization, and hyphal formation and elongation. Importantly, all avirulent mutant strains lacked the ability to maintain proper sterol distribution. Overall, our results have established the importance of the AHD and zinc-binding domain in fungal invasion, and have correlated an avirulent phenotype with the inability to maintain proper sterol distribution

Difficulty Classification of Mountainbike Downhill Trails utilizing Deep Neural Networks

The difficulty of mountainbike downhill trails is a subjective perception. However, sports-associations and mountainbike park operators attempt to group trails into different levels of difficulty with scales like the Singletrail-Skala (S0-S5) or colored scales (blue, red, black, ...) as proposed by The International Mountain Bicycling Association. Inconsistencies in difficulty grading occur due to the various scales, different people grading the trails, differences in topography, and more. We propose an end-to-end deep learning approach to classify trails into three difficulties easy, medium, and hard by using sensor data. With mbientlab Meta Motion r0.2 sensor units, we record accelerometer- and gyroscope data of one rider on multiple trail segments. A 2D convolutional neural network is trained with a stacked and concatenated representation of the aforementioned data as its input. We run experiments with five different sample- and five different kernel sizes and achieve a maximum Sparse Categorical Accuracy of 0.9097. To the best of our knowledge, this is the first work targeting computational difficulty classification of mountainbike downhill trails.Comment: 11 pages, 5 figure

Anaerobic Carbon Monoxide Dehydrogenase Diversity in the Homoacetogenic Hindgut Microbial Communities of Lower Termites and the Wood Roach

Anaerobic carbon monoxide dehydrogenase (CODH) is a key enzyme in the Wood-Ljungdahl (acetyl-CoA) pathway for acetogenesis performed by homoacetogenic bacteria. Acetate generated by gut bacteria via the acetyl-CoA pathway provides considerable nutrition to wood-feeding dictyopteran insects making CODH important to the obligate mutualism occurring between termites and their hindgut microbiota. To investigate CODH diversity in insect gut communities, we developed the first degenerate primers designed to amplify cooS genes, which encode the catalytic (β) subunit of anaerobic CODH enzyme complexes. These primers target over 68 million combinations of potential forward and reverse cooS primer-binding sequences. We used the primers to identify cooS genes in bacterial isolates from the hindgut of a phylogenetically lower termite and to sample cooS diversity present in a variety of insect hindgut microbial communities including those of three phylogenetically-lower termites, Zootermopsis nevadensis, Reticulitermes hesperus, and Incisitermes minor, a wood-feeding cockroach, Cryptocercus punctulatus, and an omnivorous cockroach, Periplaneta americana. In total, we sequenced and analyzed 151 different cooS genes. These genes encode proteins that group within one of three highly divergent CODH phylogenetic clades. Each insect gut community contained CODH variants from all three of these clades. The patterns of CODH diversity in these communities likely reflect differences in enzyme or physiological function, and suggest that a diversity of microbial species participate in homoacetogenesis in these communities